Donald Trump’s retribution tour against members of his own party is already backfiring.

This week, Louisiana Sen. Bill Cassidy and Kentucky Rep. Thomas Massie lost their primaries to Trump-backed challengers. Then, the president endorsed incumbent Texas Sen. John Cornyn’s primary opponent, Ken Paxton, angering many Republicans who believe a Paxton candidacy could put Texas in play in November.

By working to oust members of his party, Trump is needlessly antagonizing allies on Capitol Hill and making it harder to pass his agenda, many Republican lawmakers believe. A growing number of them are breaking with Trump, especially those who now feel unburdened by the pressures of reelection and can speak out freely.

On Thursday, frustration with Trump boiled over and helped derail an immigration spending bill the president had demanded months ago. Senators then packed up and left town for a weeklong recess with no indication of when or how they’ll be able to pass the legislation when they return next month.

“It’s hard to divorce anything that happens here from what’s happening in the political atmosphere around us,” Senate Majority Leader John Thune acknowledged afterward, referring to Trump’s campaign interventions. “You can’t disconnect those things.”

Republicans rebelled against two of Trump’s top priorities he wanted to see tucked into the reconciliation bill: $1 billion in taxpayer funding for Secret Service and a new White House ballroom, and an unlimited new $1.8 billion fund to compensate purported victims of prosecutorial overreach under President Joe Biden. The opposition to both ranged widely across the conference, preventing Republican leaders from holding a vote on the immigration package.

“So the nation’s top law enforcement official is asking for a slush fund to pay people who assault cops? Utterly stupid, morally wrong – Take your pick,” Kentucky Sen. Mitch McConnell said in a fiery statement aimed at acting Attorney General Todd Blanche, who met with skeptical Republicans senators on Thursday.

North Carolina Sen. Thom Tillis, who at times has been a lonely Republican critic of Trump’s policies, said he welcomed more members to his club, which has been dubbed the YOLO or “you only live once” caucus.

“I hope that they will be motivated, like I am, to stop [us] running into the ditch and making it more difficult for Republicans to get reelected or elected in November,” Tillis, who is retiring at the end of the year, told NOTUS.

“I think there will be fewer political calculations going into people’s decision-making process,” he added of his jilted colleagues. “We want to support the president every time it’s good policy and good politics, and never when it’s either bad policy or bad politics.”

Cassidy hasn’t wasted any time making his voice heard — one day after losing his primary this week, the senator cast the deciding vote to advance legislation aimed at ending hostilities with Iran, in a big rebuke to the White House. He also slammed Trump’s ballroom, as well as the idea of compensating people convicted of participating in the Jan. 6, 2021, riot at the U.S. Capitol with taxpayer money, many of whom have vowed to apply to the DOJ fund.

“That’s not right, and if it’s not right, we shouldn’t be doing it,” Cassidy told NOTUS.

Cornyn could soon join the YOLO caucus. The Texas Republican is still holding out hope he can prevail against Paxton in the state’s primary runoff next week, but with Trump endorsing against him, he’s in big trouble. Paxton led in polls even before the president’s endorsement.

If Cornyn loses next week, he, too, might be unburdened once the Senate returns and takes up the immigration bill again.

Trump went against the wishes of Senate Republican leaders by snubbing Cornyn. Their job keeping their 53-member conference united for the rest of this year and making sure they retain a majority next year is now even more difficult.

“There’s always a consequence associated with taking on an incumbent United States senator,” Thune told reporters Wednesday. “He obviously has his favorites and people he wants to endorse, and it’s his prerogative, but what we have to deal with up here is moving the agenda, and you know, obviously that can become slightly more complicated.”

The White House insists that, despite his meddling, Trump remains committed to maintaining Republicans’ edge in the chamber.

“President Trump is the unequivocal leader, best messenger, and unmatched motivator for the Republican party and he is committed to maintaining Republicans’ majority in Congress to continue delivering wins for the American people,” White House spokesperson Olivia Wales said in a statement.

In addition to trouble rounding up GOP votes for nominations and this week’s reconciliation package that includes funding for immigration enforcement, Republicans could face a math problem on future legislation, including another reconciliation package that some in the party are demanding to address affordability and rising costs ahead of the midterm elections.

“It’s simply a matter of individuals who right now are sharing what they think is the best path forward, and I think it was pretty easy to see that as a possibility from a long ways back,” said Thune’s fellow South Dakotan, Sen. Mike Rounds.

Alaska Sen. Lisa Murkowski said she couldn’t understand why Trump couldn’t see that torpedoing Senate Republicans hurts his agenda and their ability to govern.

“Why would you go against members of your own team?” she wondered. “I don’t think that it benefits the president at all. I just don’t understand his calculus in being personally vindictive towards Republicans. It seems like he’s expending more of his dissatisfaction about members of Congress directed towards Republicans and not Democrats.”